Found 11 matching trials
Ribociclib and Endocrine Therapy or Chemotherapy With or Without Bevacizumab for Metastatic Breast Cancer in First Line PHASE3 This study is designed to evaluate the efficacy and safety of first-line tr...
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Gemeinschaftspraxis für Hämatologie und Onkologie
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Endocrine Therapy Plus CDK4/6 in First or Second Line for Hormone (SONIA) Receptor Positive Advanced Breast Cancer PHASE3 Given the uncertain benefit in efficacy of adding CDK 4/6 to first rather t...
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Active Not Recruiting
Location
Jeroen Bosch Ziekenhuis
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Phase 1b/2 Study of TTI-101 in Combination for Patients With Metastatic Hormone Receptor-Positive and HER2-Negative Breast Cancer PHASE1 The primary objective of Phase 1b will be to evaluate the safety and tolera...
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Holy Cross Health Fort Lauderdale - Holy Cross Hospital
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Aromatase Inhibitor Therapy With or Without Fulvestrant for the Treatment of HR Positive Metastatic Breast Cancer With an ERS1 Activating Mutation, the INTERACT Study PHASE2 This phase II trial studies how well letrozole, anastrozole, or fulvestrant...
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M D Anderson Cancer Center
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Efficacy and Safety of Trastuzumab Rezetecan Followed by CDK4/6 Inhibitors and Endocrine Therapy in HR+/HER2-Low/Ultra-Low Advanced Breast Cancer PHASE2 This multicenter, prospective phase II clinical trial evaluates the efficac...
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Sun Yat-sen Memorial Hospital
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First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors PHASE1 Study STX-478-101 (LY4064809) is a multipart, open-label, phase 1/2 study e...
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Ellison Clinic at Saint John's
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Analysis of Therapy Sequence in Women With HR+, HER2 - mBC in Moscow: A Multicenter Retrospective Observational Study. N/A A assessment of the efficacy of first-/second-line endocrine therapies ± ta...
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N.N. Blokhin National Medical Research Center of Oncology
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Phase I/Ib Trial of LSZ102 Single Agent or LSZ102 + LEE011 or LSZ102 + BYL719 in ER+ Breast Cancers PHASE1 To characterize the safety and tolerability, identify recommended doses and...
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Massachusetts General Hospital Massachusetts General Hospital
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T-DM1 Combined With CDK4/6 Inhibitor Ribociclib PHASE2 To explore the efficacy and safety of T-DM1 combined with CDK4/6 inhibitor ...
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Enrolling By Invitation
Location
Zhejiang Cancer Hospital
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Study of AVZO-021 in Patients With Advanced Solid Tumors PHASE1 This study, the first clinical trial of AVZO-021, aims to determine the saf...
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Yale Cancer Center
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